Mouse Atp6ap2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atp6ap2
Locus ID	70495
Kit Components	GA208541G1, Atp6ap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208541G2, Atp6ap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208541G3, Atp6ap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_027439
Synonyms	(P)RR; 5730403E06Rik; APT6M8-9; Atp6ip2; ATP6M8-9; M8-9; PRR
Summary	Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) (By similarity).[UniProtKB/Swiss-Prot Function]

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