Mouse Mier1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mier1
Locus ID	71148
Kit Components	GA208744G1, Mier1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208744G2, Mier1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208744G3, Mier1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001039081, NM_001286221, NM_001286222, NM_001286223, NM_027696
Synonyms	4933425I22Rik; 5830411K19Rik; er1
Summary	Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing.[UniProtKB/Swiss-Prot Function]

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