Mouse Pdia6 activation kit by CRISPRa
CAT#: GA208978
Pdia6 CRISPRa kit - CRISPR gene activation of mouse protein disulfide isomerase associated 6
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Pdia6 |
Locus ID | 71853 |
Kit Components | GA208978G1, Pdia6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA208978G2, Pdia6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA208978G3, Pdia6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_027959 |
Synonyms | 1700015E05Rik; AL023058; C77895; CaBP5; P5; Txndc7 |
Summary | May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:24508390). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (By similarity). May also regulate the UPR via the EIF2AK3 UPR sensor (By similarity). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN513047 | Pdia6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |