Mouse Zkscan3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zkscan3
Locus ID	72739
Kit Components	GA209329G1, Zkscan3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209329G2, Zkscan3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209329G3, Zkscan3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145778, NM_023685, NM_001368182
Synonyms	2810435N07Rik; AA408594; AI132359; mszf35; Skz1; Zf47; Zfp-47; Zfp306; Zfp307
Summary	Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters (By similarity).[UniProtKB/Swiss-Prot Function]

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