Mouse Poldip3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Poldip3
Locus ID	73826
Kit Components	GA209619G1, Poldip3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209619G2, Poldip3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209619G3, Poldip3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001347082, NM_178627
Synonyms	1110008P04Rik; AA408269; AL022852; C77954; mKIAA1649; PDIP46; SKAR
Summary	Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex (By similarity).[UniProtKB/Swiss-Prot Function]

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