Mouse Pacsin3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pacsin3
Locus ID	80708
Kit Components	GA211122G1, Pacsin3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211122G2, Pacsin3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211122G3, Pacsin3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001289677, NM_001289678, NM_028733, NM_030880
Synonyms	4921507A02Rik; 6330413E15Rik; AW413130
Summary	Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity.[UniProtKB/Swiss-Prot Function]

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