Mouse Ptpn23 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptpn23
Locus ID	104831
Kit Components	GA211838G1, Ptpn23 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211838G2, Ptpn23 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211838G3, Ptpn23 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081043
Synonyms	AI462446; PTP-TD14
Summary	Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis (By similarity).[UniProtKB/Swiss-Prot Function]

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