Mouse Mtbp activation kit by CRISPRa

CAT#: GA211898

Mtbp CRISPRa kit - CRISPR gene activation of mouse Mdm2, transformed 3T3 cell double minute p53 binding protein



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Mtbp
Locus ID 105837
Kit Components

GA211898G1, Mtbp gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211898G2, Mtbp gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211898G3, Mtbp gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001168250, NM_134092
Synonyms AI429604; MDM2BP
Summary May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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