Mouse Atp6v1h activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atp6v1h
Locus ID	108664
Kit Components	GA212121G1, Atp6v1h gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212121G2, Atp6v1h gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212121G3, Atp6v1h gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001310442, NM_133826
Synonyms	0710001F19Rik; AU022349; CGI-11; SFD; SFDalpha; SFDbeta; VMA13
Summary	Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes (By similarity).[UniProtKB/Swiss-Prot Function]

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