Mouse Dph1 activation kit by CRISPRa
CAT#: GA212466
Dph1 CRISPRa kit - CRISPR gene activation of mouse diphthamide biosynthesis 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Dph1 |
Locus ID | 116905 |
Kit Components | GA212466G1, Dph1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212466G2, Dph1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212466G3, Dph1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_144491 |
Synonyms | 2310011M22Rik; 4930488F09Rik; AW551873; Dph2l1; Ovca1 |
Summary | Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). Acts also as a tumor suppressor in lung and breast cancers. Plays a role in embryonic growth, organogenesis and postnatal survival. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN504770 | Dph1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |