Mouse Dph1 activation kit by CRISPRa

CAT#: GA212466

Dph1 CRISPRa kit - CRISPR gene activation of mouse diphthamide biosynthesis 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Dph1
Locus ID 116905
Kit Components

GA212466G1, Dph1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212466G2, Dph1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212466G3, Dph1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_144491
Synonyms 2310011M22Rik; 4930488F09Rik; AW551873; Dph2l1; Ovca1
Summary Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). Acts also as a tumor suppressor in lung and breast cancers. Plays a role in embryonic growth, organogenesis and postnatal survival. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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