Mouse Kcnn2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kcnn2
Locus ID	140492
Kit Components	GA212511G1, Kcnn2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212511G2, Kcnn2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212511G3, Kcnn2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001312905, NM_080465
Synonyms	bc; fri; KCa2.2; SK2; SKCA2
Summary	Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.[UniProtKB/Swiss-Prot Function]

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