Mouse Phf21a activation kit by CRISPRa
CAT#: GA212719
Phf21a CRISPRa kit - CRISPR gene activation of mouse PHD finger protein 21A
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Phf21a |
Locus ID | 192285 |
Kit Components | GA212719G1, Phf21a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212719G2, Phf21a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212719G3, Phf21a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001109690, NM_001109691, NM_001346704, NM_138755, NM_001362829, NM_001362830, NM_001362831, NM_001362832, NM_001362833 |
Synonyms | 80kDa; Bhc; Bhc80; D030065N23Rik; PFTF1 |
Summary | Component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it may act as a scaffold. Inhibits KDM1A-mediated demethylation of 'Lys-4' of histone H3 in vitro, suggesting a role in demethylation regulation (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN513208 | Phf21a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |