Mouse Kdm4b activation kit by CRISPRa

CAT#: GA212754

Kdm4b CRISPRa kit - CRISPR gene activation of mouse lysine (K)-specific demethylase 4B



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Kdm4b
Locus ID 193796
Kit Components

GA212754G1, Kdm4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA212754G2, Kdm4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA212754G3, Kdm4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_172132, NM_001357909
Synonyms 4732474L06Rik; Jmjd2b; mKIAA0876
Summary Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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