Mouse Tmem259 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem259
Locus ID	216157
Kit Components	GA213327G1, Tmem259 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213327G2, Tmem259 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213327G3, Tmem259 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001003949, NM_001359632
Synonyms	AC087114.7gm2; mFLJ00277; ORF61; R32184_3
Summary	May have a role in the ERAD pathway required for clearance of misfolded proteins in the endoplasmic reticulum (ER). Promotes survival of motor neurons, probably by protecting against ER stress.[UniProtKB/Swiss-Prot Function]

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