Mouse Adamts2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adamts2
Locus ID	216725
Kit Components	GA213371G1, Adamts2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213371G2, Adamts2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213371G3, Adamts2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001277305, NM_175643
Synonyms	ADAM-TS2; ADAMTS-2; ADAMTS-3; hPCPNI; mKIAA4060; PCINP; pNPI
Summary	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin repeats) family of proteinases that is involved in the proteolytic processing of procollagens. The encoded protein precursor is proteolytically processed to generate a mature, zinc-dependent enzyme. Mice lacking the encoded protein develop abnormal lungs, fragile skin and male sterility. [provided by RefSeq, Aug 2015]

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