Mouse Nle1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nle1
Locus ID	217011
Kit Components	GA213411G1, Nle1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213411G2, Nle1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213411G3, Nle1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_145431
Synonyms	AL022765; BC018399; l11Jus1; l11Jus4; Nle
Summary	Plays a role in regulating Notch activity (Probable). Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival.[UniProtKB/Swiss-Prot Function]

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