Mouse Unc45b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Unc45b
Locus ID	217012
Kit Components	GA213412G1, Unc45b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213412G2, Unc45b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213412G3, Unc45b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_178680
Synonyms	AA445617; Cmya4; D230041A13Rik; Unc45
Summary	Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development (PubMed:12356907, PubMed:18326487, PubMed:18478096). Is necessary for normal early lens development (By similarity).[UniProtKB/Swiss-Prot Function]

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