Mouse Erlin1 activation kit by CRISPRa
CAT#: GA213830
Erlin1 CRISPRa kit - CRISPR gene activation of mouse ER lipid raft associated 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Erlin1 |
Locus ID | 226144 |
Kit Components | GA213830G1, Erlin1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213830G2, Erlin1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213830G3, Erlin1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001164359, NM_001164360, NM_145502 |
Synonyms | 2810439N09Rik; C80197; Keo4; Spfh1 |
Summary | Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN505348 | Erlin1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |