Mouse Stradb activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Stradb
Locus ID	227154
Kit Components	GA213909G1, Stradb gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213909G2, Stradb gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213909G3, Stradb gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_172656, NR_151686, NM_173155
Synonyms	AA792893; Als2cr2; B830008M19; D1Ucla2; ILPIP; ILPIPA; Papk; PRO1038; Syradb
Summary	Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).[UniProtKB/Swiss-Prot Function]

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