Mouse Man1b1 activation kit by CRISPRa
CAT#: GA213941
Man1b1 CRISPRa kit - CRISPR gene activation of mouse mannosidase, alpha, class 1B, member 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Man1b1 |
Locus ID | 227619 |
Kit Components | GA213941G1, Man1b1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213941G2, Man1b1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213941G3, Man1b1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001029983 |
Synonyms | E430019H13Rik; ERMan1; Gm108; MANA-ER |
Summary | Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2) (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN509696 | Man1b1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |