Mouse Sptlc3 activation kit by CRISPRa
CAT#: GA214019
Sptlc3 CRISPRa kit - CRISPR gene activation of mouse serine palmitoyltransferase, long chain base subunit 3
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Sptlc3 |
Locus ID | 228677 |
Kit Components | GA214019G1, Sptlc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214019G2, Sptlc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214019G3, Sptlc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_175467, NM_001356507 |
Synonyms | C130053K05Rik |
Summary | Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. SPT complexes containing SPTLC3 generate shorter chain sphingoid bases compared to complexes containing SPTLC2. The SPTLC1-SPTLC3-SPTSSA isozyme uses C12-CoA, C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. On the other hand, the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
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KN316688 | Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated |
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KN316688BN | Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated |
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KN316688LP | Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated |
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KN316688RB | Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated |
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KN516688 | Sptlc3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |