Mouse Alkbh2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Alkbh2
Locus ID	231642
Kit Components	GA214277G1, Alkbh2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214277G2, Alkbh2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214277G3, Alkbh2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_175016, NM_001359940, NM_001359941
Synonyms	9530023G02; Abh2; AU016977; mABH2
Summary	Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine. Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.[UniProtKB/Swiss-Prot Function]

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