Mouse Clec9a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Clec9a
Locus ID	232414
Kit Components	GA214358G1, Clec9a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214358G2, Clec9a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214358G3, Clec9a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001205363, NM_001205364, NM_001205365, NM_172732
Synonyms	9830005G06Rik; DNGR-1
Summary	Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.[UniProtKB/Swiss-Prot Function]

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