Mouse P2ry6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	P2ry6
Locus ID	233571
Kit Components	GA214464G1, P2ry6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214464G2, P2ry6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214464G3, P2ry6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_183168
Synonyms	2010204J23Rik; P2Y6
Summary	Receptor for extracellular UTP > ADP = 2-methylthio-ATP > ADP-beta-S > ATP = ATP-gamma-S. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Functionally coupled to phospholipase C (By similarity).[UniProtKB/Swiss-Prot Function]

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