Mouse Ndrg4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ndrg4
Locus ID	234593
Kit Components	GA214544G1, Ndrg4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214544G2, Ndrg4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214544G3, Ndrg4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001195006, NM_145602
Synonyms	D8Bwg1337e; Ndr1-rs; Ndr4; R74996; SMAP-8
Summary	Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress. May enhance growth factor-induced ERK1 and ERK2 phosphorylation. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.[UniProtKB/Swiss-Prot Function]

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