Mouse Slc17a5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc17a5
Locus ID	235504
Kit Components	GA214634G1, Slc17a5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214634G2, Slc17a5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214634G3, Slc17a5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001276452, NM_172773
Synonyms	4631416G20Rik; 4732491M05; AST; ISSD; NSD; SD; SIALIN; SIASD; SLD
Summary	Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential-dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed and secreted in saliva (By similarity).[UniProtKB/Swiss-Prot Function]

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