Mouse Dock4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dock4
Locus ID	238130
Kit Components	GA214778G1, Dock4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214778G2, Dock4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214778G3, Dock4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_172803
Synonyms	5330406C03; 6330411N01Rik; AF263288; C030023J22; mKIAA0716
Summary	Involved in regulation of adherens junction between cells. Plays a role in cell migration. Functions as a guanine nucleotide exchange factor (GEF), which activates Rap1 small GTPase by exchanging bound GDP for free GTP (By similarity).[UniProtKB/Swiss-Prot Function]

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