Mouse Arhgap22 activation kit by CRISPRa

CAT#: GA214823

Arhgap22 CRISPRa kit - CRISPR gene activation of mouse Rho GTPase activating protein 22



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Arhgap22
Locus ID 239027
Kit Components

GA214823G1, Arhgap22 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA214823G2, Arhgap22 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA214823G3, Arhgap22 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_153800
Synonyms B230341L19Rik; p68RacGAP; RHOGAP2
Summary Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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