Mouse Gphn activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gphn
Locus ID	268566
Kit Components	GA215937G1, Gphn gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215937G2, Gphn gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215937G3, Gphn gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_145965, NM_172952
Synonyms	5730552E08Rik; AI662856; BC027112; C230040D23; geph; GPH; GPHRYN
Summary	Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.[UniProtKB/Swiss-Prot Function]

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