Mouse Agxt2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Agxt2
Locus ID	268782
Kit Components	GA215954G1, Agxt2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215954G2, Agxt2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215954G3, Agxt2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001031851, NM_001310735, NM_001310736
Synonyms	AI303810; AI663818
Summary	Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure.[UniProtKB/Swiss-Prot Function]

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