Mouse Irf2bp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Irf2bp1
Locus ID	272359
Kit Components	GA216127G1, Irf2bp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216127G2, Irf2bp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216127G3, Irf2bp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_178757
Synonyms	6330414O09Rik; C530033F24
Summary	Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.[UniProtKB/Swiss-Prot Function]

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