Mouse Cadps2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cadps2
Locus ID	320405
Kit Components	GA216483G1, Cadps2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216483G2, Cadps2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216483G3, Cadps2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001252105, NM_001252106, NM_001252107, NM_001252108, NM_001252109, NM_001252110, NM_153163
Synonyms	A230044C21Rik; Caps-2; Caps2; Cpd2
Summary	Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles.[UniProtKB/Swiss-Prot Function]

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