Mouse Vwc2l activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vwc2l
Locus ID	320460
Kit Components	GA216494G1, Vwc2l gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216494G2, Vwc2l gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216494G3, Vwc2l gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001310658, NM_177164
Synonyms	A830006F12Rik; Brl
Summary	May play a role in neurogenesis. May promote matrix mineralization (PubMed:22209847), but has been shown to weakly, but significantly inhibit BMP2 and BMP6 activity in a preosteoblastic cell line (PubMed:19852960).[UniProtKB/Swiss-Prot Function]

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