Mouse Tmem67 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem67
Locus ID	329795
Kit Components	GA216771G1, Tmem67 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216771G2, Tmem67 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216771G3, Tmem67 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_177861, NR_110955
Synonyms	5330408M12Rik; b2b1163.1Clo; b2b1291.1Clo; B230117O07
Summary	Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (sftpc).[UniProtKB/Swiss-Prot Function]

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