Mouse Sgpp2 activation kit by CRISPRa
CAT#: GA217548
Sgpp2 CRISPRa kit - CRISPR gene activation of mouse sphingosine-1-phosphate phosphotase 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Sgpp2 |
Locus ID | 433323 |
Kit Components | GA217548G1, Sgpp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217548G2, Sgpp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217548G3, Sgpp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001004173 |
Synonyms | Spp2; SPPase2 |
Summary | Has specific phosphohydrolase activity towards sphingoid base 1-phosphates. Has high phosphohydrolase activity against dihydrosphingosine-1-phosphate and sphingosine-1-phosphate (S1P) in vitro (Probable). Sphingosine-1-phosphate phosphatase activity is needed for efficient recycling of sphingosine into the sphingolipid synthesis pathway (By similarity). May play a role in attenuating intracellular sphingosine 1-phosphate (S1P) signaling. May play a role in pro-inflammatory signaling (By similarity). Plays a role in the regulation of pancreatic islet beta-cell endoplasmic reticulum stress and proliferation (PubMed:27059959).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN515689 | Sgpp2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |