Mouse Arhgef15 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Arhgef15
Locus ID	442801
Kit Components	GA217708G1, Arhgef15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217708G2, Arhgef15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217708G3, Arhgef15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_177566, NM_001364772
Synonyms	D130071N09; D530030K12Rik; E5
Summary	Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.[UniProtKB/Swiss-Prot Function]

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