SATB1 Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA	RFP-BSD
Symbol	SATB1
Locus ID	6304
Kit Components	KN200421G1, SATB1 gRNA vector 1 in pCas-Guide CRISPR vector KN200421G2, SATB1 gRNA vector 2 in pCas-Guide CRISPR vector KN200421RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001131010, NM_001195470, NM_002971, NM_001322871, NM_001322872, NM_001322873, NM_001322874, NM_001322875, NM_001322876
Synonyms	DNA-binding protein SATB1; SATB homeobox 1; special AT-rich sequence binding protein 1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)
Summary	This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. [provided by RefSeq, Apr 2016]

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