NFIB Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA	Luciferase-Puro
Symbol	NFIB
Locus ID	4781
Kit Components	KN201590G1, NFIB gRNA vector 1 in pCas-Guide CRISPR vector KN201590G2, NFIB gRNA vector 2 in pCas-Guide CRISPR vector KN201590LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001190737, NM_001190738, NM_001282787, NM_005596, NM_001369458, NM_001369459, NM_001369460, NM_001369463, NM_001369464, NM_001369465, NM_001369466, NM_001369467, NM_001369472, NM_001369473, NM_001369474, NM_001369475, NM_001369476, NM_001369480, NM_001369481, NR_161385, NM_001369461, NM_001369462, NM_001369468, NM_001369469, NM_001369470, NM_001369471, NM_001369477, NM_001369478, NM_001369479, NR_161382, NR_161383, NR_161384
Synonyms	CTF; HMGIC/NFIB; NF-I/B; NF1-B; NFI-B; NFI-RED; NFIB2; NFIB3
Summary	Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.[UniProtKB/Swiss-Prot Function]

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