PAM Human Gene Knockout Kit (CRISPR)
CAT#: KN202074BN
PAM - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
CNY 3,710.00
CNY 6,344.00
CNY 7,130.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | PAM |
Locus ID | 5066 |
Kit Components |
KN202074G1, PAM gRNA vector 1 in pCas-Guide CRISPR vector KN202074G2, PAM gRNA vector 2 in pCas-Guide CRISPR vector KN202074BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000919, NM_001177306, NM_001319943, NM_138766, NM_138821, NM_138822, NR_033440, NM_001364582, NM_001364584, NM_001364586, NM_001364588, NM_001364589, NM_001364590, NM_001364593, NM_001364583, NM_001364585, NM_001364587, NM_001364591, NM_001364592, NM_001364594, NR_157231 |
Synonyms | PAL; PHM |
Summary | This gene encodes a multifunctional protein. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme includes two domains with distinct catalytic activities, a peptidylglycine alpha-hydroxylating monooxygenase (PHM) domain and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL) domain. These catalytic domains work sequentially to catalyze the conversion of neuroendocrine peptides to active alpha-amidated products. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN202074 | PAM - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN202074LP | PAM - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN202074RB | PAM - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN402074 | PAM - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
|
GA103382 | PAM CRISPRa kit - CRISPR gene activation of human peptidylglycine alpha-amidating monooxygenase |
CNY 12,255.00 |