TCPTP (PTPN2) Human Gene Knockout Kit (CRISPR)
CAT#: KN202161LP
PTPN2 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
CNY 3,710.00
CNY 3,656.00
CNY 3,990.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | TCPTP |
Locus ID | 5771 |
Kit Components |
KN202161G1, TCPTP gRNA vector 1 in pCas-Guide CRISPR vector KN202161G2, TCPTP gRNA vector 2 in pCas-Guide CRISPR vector KN202161LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001207013, NM_001308287, NM_002828, NM_080422, NM_080423 |
Synonyms | PTN2; PTPT; TC-PTP; TCELLPTP; TCPTP |
Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN202161 | PTPN2 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN202161BN | PTPN2 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN202161RB | PTPN2 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN402161 | PTPN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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GA103920 | PTPN2 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase non-receptor type 2 |
CNY 12,255.00 |