CAMK2G Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	CAMK2G
Locus ID	818
Kit Components	KN205437G1, CAMK2G gRNA vector 1 in pCas-Guide CRISPR vector KN205437G2, CAMK2G gRNA vector 2 in pCas-Guide CRISPR vector KN205437BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001204492, NM_001222, NM_001320898, NM_172169, NM_172170, NM_172171, NM_172172, NM_172173, NM_001367547, NM_001367516, NM_001367518, NM_001367525, NM_001367526, NM_001367529, NM_001367534, NM_001367537, NM_001367539, NM_001367540, NM_001367542, NM_001367544, NM_001367545, NR_160042, NR_160045, NR_160263, NM_001367514, NM_001367517, NM_001367519, NM_001367520, NM_001367521, NM_001367522, NM_001367523, NM_001367524, NM_001367527, NM_001367528, NM_001367530, NM_001367531, NM_001367532, NM_001367533, NM_001367535, NM_001367536, NM_001367538, NM_001367541, NM_001367543, NM_001367546, NM_001367548, NR_160040, NR_160041, NR_160044, NR_160046, NR_160047
Synonyms	CAMK; CAMK-II; CAMKG
Summary	The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined.[provided by RefSeq, Mar 2011]

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