CAMK2D Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	CAMK2D
Locus ID	817
Kit Components	KN207454G1, CAMK2D gRNA vector 1 in pCas-Guide CRISPR vector KN207454G2, CAMK2D gRNA vector 2 in pCas-Guide CRISPR vector KN207454BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001221, NM_001321566, NM_001321567, NM_001321568, NM_001321569, NM_001321570, NM_001321571, NM_001321572, NM_001321573, NM_001321574, NM_001321575, NM_001321576, NM_001321577, NM_001321578, NM_001321579, NM_001321580, NM_001321581, NM_001321582, NM_001321583, NM_001321584, NM_001321585, NM_001321586, NM_001321587, NM_001321588, NM_001321589, NM_001321590, NM_001321591, NM_001321592, NM_172114, NM_172115, NM_172127, NM_172128, NM_172129
Synonyms	CAMKD
Summary	The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.[provided by RefSeq, Nov 2008]

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