Jagged1 (JAG1) Human Gene Knockout Kit (CRISPR)

CAT#: KN210516RB

JAG1 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
4周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


JAG1 mouse monoclonal antibody, clone OTI3A10 (formerly 3A10)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


JAG1 (Myc-DDK-tagged)-Human jagged 1 (JAG1)
    • 10 ug

CNY 12,720.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Jagged1
Locus ID 182
Kit Components

KN210516G1, Jagged1 gRNA vector 1 in pCas-Guide CRISPR vector

KN210516G2, Jagged1 gRNA vector 2 in pCas-Guide CRISPR vector

KN210516RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000214
Synonyms AGS; AHD; AWS; CD339; HJ1; JAGL1
Summary The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Nov 2019]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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