MPRIP Human Gene Knockout Kit (CRISPR)
CAT#: KN211386BN
MPRIP - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
CNY 3,710.00
CNY 19,855.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | MPRIP |
Locus ID | 23164 |
Kit Components |
KN211386G1, MPRIP gRNA vector 1 in pCas-Guide CRISPR vector KN211386G2, MPRIP gRNA vector 2 in pCas-Guide CRISPR vector KN211386BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_015134, NM_201274, NM_001364716 |
Synonyms | M-RIP; MRIP; p116Rip; RHOIP3; RIP3 |
Summary | Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN211386 | MPRIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN211386LP | MPRIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN211386RB | MPRIP - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN411386 | MPRIP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
|
GA108086 | MPRIP CRISPRa kit - CRISPR gene activation of human myosin phosphatase Rho interacting protein |
CNY 12,255.00 |