CTIP2 (BCL11B) Human Gene Knockout Kit (CRISPR)

CAT#: KN211430LP

BCL11B - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


CTIP2/BCL11B Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


BCL11B (Myc-DDK-tagged)-Human B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B), transcript variant 1
    • 10 ug

CNY 6,552.00
CNY 7,130.00

Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol CTIP2
Locus ID 64919
Kit Components

KN211430G1, CTIP2 gRNA vector 1 in pCas-Guide CRISPR vector

KN211430G2, CTIP2 gRNA vector 2 in pCas-Guide CRISPR vector

KN211430LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001282237, NM_001282238, NM_022898, NM_138576
Synonyms ATL1; ATL1-alpha; ATL1-beta; ATL1-delta; ATL1-gamma; CTIP-2; CTIP2; hRIT1-alpha; RIT1; ZNF856B
Summary This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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