CDK8 Human Gene Knockout Kit (CRISPR)
CAT#: KN212592LP
CDK8 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | CDK8 |
Locus ID | 1024 |
Kit Components |
KN212592G1, CDK8 gRNA vector 1 in pCas-Guide CRISPR vector KN212592G2, CDK8 gRNA vector 2 in pCas-Guide CRISPR vector KN212592LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001260, NM_001318368, NM_001346501 |
Synonyms | K35 |
Summary | This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
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KN212592 | CDK8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN212592BN | CDK8 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN212592RB | CDK8 - human gene knockout kit via CRISPR, HDR mediated |
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KN412592 | CDK8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
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