YAP1 Human Gene Knockout Kit (CRISPR)
CAT#: KN214393RB
YAP1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | YAP1 |
Locus ID | 10413 |
Kit Components |
KN214393G1, YAP1 gRNA vector 1 in pCas-Guide CRISPR vector KN214393G2, YAP1 gRNA vector 2 in pCas-Guide CRISPR vector KN214393RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001130145, NM_001195044, NM_001195045, NM_001282097, NM_001282098, NM_001282099, NM_001282100, NM_001282101, NM_006106 |
Synonyms | COB1; YAP; YAP2; YAP65; YKI |
Summary | This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
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KN214393 | YAP1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN214393BN | YAP1 - human gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN214393LP | YAP1 - human gene knockout kit via CRISPR, HDR mediated |
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KN414393 | YAP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
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