Protein Kinase D2 (PRKD2) Human Gene Knockout Kit (CRISPR)

CAT#: KN214956BN

PRKD2 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

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CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Anti-PRKD2 (Protein Kinase D2) mouse monoclonal antibody, clone OTI5G1 (formerly 5G1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


PRKD2 (Myc-DDK-tagged)-Human protein kinase D2 (PRKD2), transcript variant 1
    • 10 ug

CNY 6,432.00
CNY 7,130.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol Protein Kinase D2
Locus ID 25865
Kit Components

KN214956G1, Protein Kinase D2 gRNA vector 1 in pCas-Guide CRISPR vector

KN214956G2, Protein Kinase D2 gRNA vector 2 in pCas-Guide CRISPR vector

KN214956BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001079880, NM_001079881, NM_001079882, NM_016457
Synonyms HSPC187; nPKC-D2; PKD2
Summary The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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