Periostin (POSTN) Human Gene Knockout Kit (CRISPR)

CAT#: KN215156RB

POSTN - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


POSTN mouse monoclonal antibody, clone OTI2B2 (formerly 2B2)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


POSTN (Myc-DDK-tagged)-Human periostin, osteoblast specific factor (POSTN), transcript variant 3
    • 10 ug

CNY 8,576.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Periostin
Locus ID 10631
Kit Components

KN215156G1, Periostin gRNA vector 1 in pCas-Guide CRISPR vector

KN215156G2, Periostin gRNA vector 2 in pCas-Guide CRISPR vector

KN215156RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001135934, NM_001135935, NM_001135936, NM_001286665, NM_001286666, NM_001286667, NM_001330517, NM_006475
Synonyms OSF-2; OSF2; PDLPOSTN; PN
Summary This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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