USP6 Human Gene Knockout Kit (CRISPR)

CAT#: KN215749RB

USP6 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Goat Anti-USP6 / TRE2 / TRE17 Antibody
    • 100 ug

CNY 5,371.00


USP6 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 6 (Tre-2 oncogene) (USP6)
    • 10 ug

CNY 9,624.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol USP6
Locus ID 9098
Kit Components

KN215749G1, USP6 gRNA vector 1 in pCas-Guide CRISPR vector

KN215749G2, USP6 gRNA vector 2 in pCas-Guide CRISPR vector

KN215749RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001039674, NM_001304284, NM_004505, NM_005152
Synonyms HRP1; Tre-2; TRE2; TRE17
Summary Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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